Ars Technica +3GE AdvancesAI-designed proteases cut proteins at chosen sites — Show the summaryA team led by David Baker used AI to design zinc proteases that cut selected peptide bonds. Optimised variants sped up the reaction by more than ten billion times compared with the uncatalysed reaction.
Northwestern Now +3NN LongevityOvaries continue to remodel for decades after menopause — Show the summaryThe Aging Cell study analysed ovaries from women aged 50 to 75. Some molecular signals resembled those in ovarian cancer, but the small cross-sectional sample establishes neither causation nor surgical implications.
Nature +3RU LongevityIn 101,243 patients, brown fat is linked to fewer cardiometabolic and mental health conditions — Show the summaryUsing PET-CT scans, the study found associations with favourable blood sugar, lipid and inflammation profiles. Losartan increased activity and energy expenditure in experimental models; the patient findings remain observational.
Open House New York +3OHNSNNGO CultureOpen House New York Weekend begins with more than 300 venues open — Show the summaryOpen House New York Weekend begins today. More than 300 venues across the five boroughs, including workplaces and cultural spaces, will open to the public for three days of tours and behind-the-scenes activities.
Mid-Market Business Association & Foundation +2MMBSFCKQ CultureSan Francisco launches arts and theatre district on Market Street — Show the summarySan Francisco has announced a pilot for the Market Street Arts & Theater District. The partnership aims to use one or two vacant spaces for rehearsals, production, training and independent cultural programming.
Research Le Scienze +1 LongevityGenetic toolkit controls added genes in activated T cells — Show the summaryA group led by IIT describes synthetic promoters designed to control genes added to activated or chronically stimulated T cells.
usa.chinadaily.com.cn +2UCCGWE AdvancesChina installs more than 7 GW of offshore wind in 2025 — Show the summaryChina installed more than 7 GW of new offshore wind capacity in 2025, according to the National Energy Administration, cited by China Daily. This was nearly 80% of the reported global annual total.
Dezeen +4CD AdvancesTesla shows Roadster prototype using air thrusters in brief flight — Show the summaryAt a live event in Texas, the prototype travelled over ramps and briefly flew using compressed-air thrusters. The demonstration and performance data have not been independently confirmed.
Hugging Face +2AANNNR AdvancesNVIDIA and AI4Bharat announce 2.8-trillion-token corpus for Indian languages — Show the summaryAccording to NVIDIA and AI4Bharat/IIT Madras, the synthetic corpus is for pre-training and covers 34 language-script configurations. Primary documentation and verification of licensing, publication and evaluations are still lacking.
ABC +2FTSPA LongevityFijian conjoined twins separated in Saudi Arabia at 13 months — Show the summaryA team at King Abdullah Specialist Children’s Hospital has separated twin girls joined at the lower abdomen and pelvis. The operation took place in nine stages and began anatomical reconstruction.
Research PPRPP AdvancesPreprint maps AI methods and limits in drug discovery — Show the summaryThe preprint reviews AI methods and evaluation practices in drug discovery across 618 peer-reviewed studies. It describes limits in reproducibility, dataset transparency and external validation; it does not show a transformation of…
Research The Conversation +1PLOS LongevityReplacing 10% of ultra-processed food is linked to fewer colorectal cancers — Show the summaryThe observational analysis used dietary questionnaires and more than 20 years of follow-up. It does not establish causation; the primary paper should be checked for uncertainty, adjustments, limitations and conflicts of interest.
Ars Technica +3HBKC AdvancesKDE releases Plasma 6.8, replacing new native X11 sessions with Wayland — Show the summaryKDE has released Plasma 6.8. The release stops new native X11 sessions from launching in favour of Wayland, and adds features for remote desktops and system management.
Hardware Upgrade +3HUTETE AdvancesMicrosoft says Windows 11 is up to 20% more responsive in its tests — Show the summaryMicrosoft says it has introduced optimisations in Windows 11. In its tests, some interface tasks can be up to 20% more responsive and use less memory, especially on PCs with 8 GB of RAM.
''The Guardian'' +4 AdvancesDelegates reportedly vote to end future leap seconds — Show the summaryDelegates at the International Bureau of Weights and Measures reportedly voted to make UTC continuous. The official resolution and confirmation of implementation details are still needed.
BBC News +2BBCMDE AdvancesNew Yalu bridge opens between China and North Korea — Show the summaryAccording to Chinese state media cited by the BBC, the bridge adds capacity for border crossings and trade. Traffic and operating arrangements remain to be seen, and a primary source is needed to confirm it has entered service.
Research Popular Science +4 AdvancesStudy estimates a chartreuse-green white dwarf from its spectrum — Show the summaryThe study, reported as published in RAS Techniques and Instruments, converts white-dwarf spectra into colours perceptible to the human eye.
Interesting Engineering +3 AdvancesPerseverance surpasses Opportunity with 45.22 kilometres travelled on Mars — Show the summaryPerseverance has reached 45.22 kilometres on Mars, surpassing Opportunity’s total distance travelled. The milestone was aided by the operational use of AutoNav autonomous navigation.
CBC +1CBCU AbundanceCarleton reportedly welcomes its first Inuit students in Indigenous journalism — Show the summaryCarleton University reportedly welcomed its first Inuit students to its Indigenous journalism programme. The available summary indicates that the primary source needs verification.
Research Greater Good +1AEL AdvancesUsing AI to challenge your own ideas may encourage critical thinking — Show the summaryA Greater Good article reports a study of 45 university knowledge workers. Analysed interviews and chats suggest that using generative AI to test ideas may encourage consideration of alternatives.
The Hindu AdvancesCommentary sees ill-defined goals behind AI incidents — Show the summaryThe commentary attributes recent incidents to poorly defined goals and operational limits. It does not portray them as autonomous agents ‘out of control’; the specific cases need independent confirmation.
Research MEDME LongevityAdaptive cancer trials have more successes, but are no faster — Show the summaryIn adaptive trials, the primary endpoint was more likely to succeed than in non-adaptive designs. The retrospective analysis of trial registries did not, however, show significantly shorter times to primary completion.
MEDME LongevityStudy confirms near absence of malaria in Timor-Leste — Show the summaryThe study measured antibodies to Plasmodium falciparum and P. vivax in 4,631 people. Seroprevalence for recent exposure was 1.4% and 0.2%, consistent with almost no ongoing transmission.
New York Times +1NGL CultureAntwerp exhibition brings together 11 of Catharina van Hemessen’s 19 known works — Show the summaryAntwerp’s Snijders&Rockoxhuis has opened the first exhibition devoted to the Van Hemessen family, with 33 works; 11 are by Catharina, out of 19 known. It runs to 31 January 2027, ahead of a Catharina-only National Gallery exhibition scheduled for March 2027.
